Severe Asthma: An Expanding and Mounting Clinical Challenge
نویسندگان
چکیده
منابع مشابه
Severe asthma: a great clinical challenge
Background Patients with severe asthma represent a significant unmet clinical need. At present, the underlying mechanisms of severe asthma have not been established yet but it is likely they reflect a heterogenous pattern rather than a single unifying process. The aim of this study is to assess the prevalence of severe asthma as well as the clinical and physiologic characteristics of patients a...
متن کاملClinical review: Severe asthma
Severe asthma, although difficult to define, includes all cases of difficult/therapy-resistant disease of all age groups and bears the largest part of morbidity and mortality from asthma. Acute, severe asthma, status asthmaticus, is the more or less rapid but severe asthmatic exacerbation that may not respond to the usual medical treatment. The narrowing of airways causes ventilation perfusion ...
متن کاملClinical phenotypes of severe asthma.
OBJECTIVE To characterize clinical phenotypes of severe asthma. METHODS A total of 111 patients were retrospectively evaluated at a specialized outpatient clinic. A systematic protocol for patient evaluation and follow-up was applied. Treatment compliance and control of the disease at the end of follow-up were defined by clinical and functional data. Patients who did not meet asthma control c...
متن کاملComparison of Seroflu and Seretide Inhalers on Spirometry Criteria and Clinical Symptoms in Patients with Severe and Moderate Asthma
Background and purpose: Asthma is one of the most prevalent chronic respiratory diseases which has become more prevalent over the past three decades. Seroflo and Seretide are inhalers that contain fluticasone (an anti-inflammatory corticosteroid) and salmeterol (a long-acting bronchodilator). This study aimed to compare the effects of Seroflo and Seretide nasal sprays on spirometry criteria and...
متن کاملP74 - Brittle asthma: a clinical phenotype of severe asthma
Background The term Brittle Asthma was generally used to describe those patients with sudden, severe attacks, usually out of the blue. Recently the following classification was suggested: type 1 characterized by a maintained wide PEF variability despite medical therapy, and type 2 characterized by sudden acute attacks on a background of apparently normal airway function. Patients who develop su...
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ژورنال
عنوان ژورنال: The Journal of Allergy and Clinical Immunology: In Practice
سال: 2013
ISSN: 2213-2198
DOI: 10.1016/j.jaip.2013.01.005